Web描述. Rabbit Monoclonal Antibody to ERK1. 研究背景. Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42). Growth factors, steroid hormones, G protein-coupled receptor ligands and neurotransmitters can initiate … WebMay 31, 2024 · SQSTM1 KD (*) was the top second hit in proteomics, however, SQSTM1 KD in the K562 ATF6 reporter cell line did not render cells resistant to Ceapin treatment and retained a similar response to negative control cells. I, input; FT, flow-through; E, elution.
ATF-6 (D4Z8V) Rabbit mAb Cell Signaling Technology
WebGlioblastoma (GBM) has a dismal prognosis and successful elimination of GBM stem cells (GSCs) is a high-priority as these cells are responsible for tumor regrowth following therapy and ultimately patient relapse. Natural products and their WebApr 5, 2024 · VU0359595 (also known as CID-53361951 or ML-270) is a potent and selective phospholipase D1 (PLD1) inhibitor. VU0359595 is >1700-fold selective for PLD1 over PLD2. This compound has various biological activities. For example, VU0359595 inhibits basal and FCS/IGF-1 stimulated proliferation of astroglial cells. Meanwhile, it … taxe hectolitre
A novel role of ER stress signal transducer ATF6 in regulating ...
WebAug 1, 2024 · ATF6 regulates ER protein folding capacity by promoting the expression of ER chaperones such as the 78-kDa glucose-regulated protein (GRP78). ER-resident chaperones like GRP78 prevent and/or resolve ER polypeptide accumulation and subsequent ER stress-induced UPR activation by folding nascent polypeptides. WebATF6 is a key transcriptional activator of the unfolded protein response (UPR), which allows mammalian cells to maintain cellular homeostasis when they are subjected to a variety of … WebOct 29, 2015 · 1 Bioarchitect Research Group, Institute of Physical and Chemical Research, Wako, Saitama 351-0198, Japan2 Cellular and Molecular Biology Laboratory, Institu ... ,干细胞之家 - 中国干细胞行业门户第一站 taxe habitation rochefort