WebCFTR - CF transmembrane conductance regulator. This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. WebThe CFTR gene provides instructions for making a protein called the CF transmembrane conductance regulator (CFTR). This protein functions as a channel across the membrane of cells that produce mucus, sweat, saliva, tears, and digestive enzymes. The channel transports negatively charged particles called chloride ions into and out of cells. The ...
CFTR gene: MedlinePlus Genetics
WebSep 12, 2024 · Cystic fibrosis (CF) is an autosomal recessive disorder common among Caucasians, whereby CFTR (Cystic Fibrosis Conductance Regulator gene), which normally encodes for an ATP-gated chloride channel, is mutated, causing the protein to misfold and not be transported to the cell membrane to perform its functions. The CFTR protein … WebMay 7, 2024 · Control of systemic acid–base homeostasis is vital for almost all physiological functions and is safeguarded by the respiratory system and the kidneys. A failure of either system causes acid–base … drilling ice holes
genetics - Functions of the CFTR gene? - Biology Stack Exchange
WebThe cystic fibrosis transmembrane conductance regulator (CFTR) protein helps to … WebDec 20, 2024 · Role of Ca 2+ Signaling in the Regulation of Cftr. In the traditional view CFTR is a cAMP activated Cl-channel as described above, however, in the recent years significant number of studies have highlighted the importance of Ca 2+ signaling and the synergism between Ca 2+ and cAMP signalization in the regulation of pancreatic … WebThe CFTR gene provides instructions for making a protein called the cystic fibrosis … drillinginfo inc