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Web27- Dada P max = 14 mV para cada uno de los diodos de la figura 2.167. determine los valores nominales de corriente maxima de cada diodo (utilizando el modelo equivalente aproximado). P max = 14mW = (0.7v) lo lo = 14 mW / 0.7 v = 20mA B- Determina lmax para v1 max= 160V R= 4.7k Ω * 56kΩ / 60.7kΩ = 4.34kΩ lmax = 160V – 0-7V /4.34k Ω lmax = … WebFeb 6, 2013 · Abstract and Figures. Sphingosine kinase isoform 1 (SK1) inhibitors may serve as therapeutic agents for proliferative diseases, including hypertension. We synthesized a series of sphingosine-based ...
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Web[32P]-ATP with over-expressed recombinant SK1 in HEK 293 cell lysates or purified SK2.15,16 By using sphingosine concentra-tions of 3 mM and 10 mM, which correspond to the K m values of SK116 and SK2,17 respectively, we demonstrate here that RB-001–003, RB-005, RB-007–009, RB-019 (Table 1), and RB-021 (Scheme 2) are selective inhibitors …
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